Tuesday, January 26, 2016

Prologue

Hi everyone.

I am Rohith Malladi and am currently a senior at BASIS Scottsdale. I have been learning at BASIS since I was in fifth grade. I have taken many classes during my education period, such as AP Biology and AP Chemistry, that I have enjoyed very much. Those two classes in particular helped me figure out what I wanted to do with my future, and more specifically, my Research Project.

This blog will document my work during the period of my Senior Research Project. The Senior Research Project is endeavor offered to senior students at BASIS Scottsdale that allows them to conduct research instead of having to come to school for the third trimester. While performing my research, I will regularly update this blog on my research, as well as with pictures, I hope. At the end of the period, I will be giving a presentation on my research and findings. Successful completion of this project results in graduation with high honors.

The research is being done through the University of Arizona Medical School and it relates to brain trauma. Specifically, we will be conducting research on translational brain trauma in mice. Recently, there have been many cases of unexplained symptoms occurring in patients who had recently suffered traumatic brain injuries.The symptoms began showing up several months after the brain injury occurred, so very few have linked the new symptoms with the brain injuries. Through our research, we wish to learn the causes of these symptoms, how to treat these symptoms, and how to prevent these symptoms from occurring during initial treatment for the traumatic brain injury.

We are currently in the animal testing stage of the research. In a separate lab, researchers are inducing brain trauma onto mice and recording their behaviors. After the behavior has been thoroughly documented, the brains of the mice are sent to our lab. We have the duty of creating slides of the brains and then analyzing the chemical and anatomical changes that occurred due to the induced brain trauma. We are hoping to discover the pharmacological causes of the delayed symptoms, and have conducted various trials. As I am only a high school intern, I have not been given access to very much hard data, but I hope that we will be able to reach some results before the end of this project period.